Neural Network Modeling of Memory Deterioration in Alzheimer's Disease
نویسندگان
چکیده
منابع مشابه
Neural Network Modeling of Memory Deterioration in Alzheimer's Disease
The clinical course of Alzheimer’s disease (AD) is generally character ized by progressive gradual deterioration, although large clinical variability exists. Motivated by the recent quantitative reports of synaptic changes in AD, we use a neural network model to investigate how the interplay between synaptic deletion and compensation determines the pattern of memory deterioration, a clinical ha...
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ژورنال
عنوان ژورنال: Neural Computation
سال: 1993
ISSN: 0899-7667,1530-888X
DOI: 10.1162/neco.1993.5.5.736